The Arab Journal of Interventional Radiology

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 3  |  Issue : 1  |  Page : 15--18

Effectiveness of percutaneous ethanol injection therapy compared to parathyroidectomy in the management of secondary and tertiary hyperparathyroidism


Inmutto Nakarin, Srisuwan Tanop, Kattipatanapong Thanate, Pochan Prach 
 Department of Radiology, Chiang Mai University, Chiang Mai, Thailand

Correspondence Address:
Dr. Inmutto Nakarin
Department of Radiology, Chiang Mai University, Chiang Mai
Thailand
Pochan Prach
Department of Radiology, Chiang Mai University, Chiang Mai
Thailand

Background: Secondary hyperparathyroidism (SHPT) and tertiary hyperparathyroidism (THPT) are a common complication of chronic renal failure. Percutaneous ethanol injection therapy (PEIT) has been used as alternative to surgery, but its effectiveness is inconsistent. Objectives: The objective of the study is to evaluate the effectiveness of PEIT in the management of patients with SHPT and THPT. Materials and Methods: Ninety-one patients with chronic renal failure and SHPT or THPT were treated with PEIT (n = 55) and surgery (n = 36) between January 2006 and July 2015. The medical records, imaging studies, and ablation techniques were reviewed to assess the efficacy of each treatment modality and complications. Results: Parathyroid hormone (PTH) level after treatment <160 pg/mL was used to indicate success of treatment. PEIT showed lower effectiveness compared to surgery (1.8% vs. 61.1%). There was no complication in PEIT group. Symptomatic hypocalcemia was found 11.1% in surgery group. Conclusion: PEIT in treatment of secondary and THPT was much less effective than surgery due to large nodule sizes, high levels of PTH, and multiple parathyroid nodules.


How to cite this article:
Nakarin I, Tanop S, Thanate K, Prach P. Effectiveness of percutaneous ethanol injection therapy compared to parathyroidectomy in the management of secondary and tertiary hyperparathyroidism.Arab J Intervent Radiol 2019;3:15-18


How to cite this URL:
Nakarin I, Tanop S, Thanate K, Prach P. Effectiveness of percutaneous ethanol injection therapy compared to parathyroidectomy in the management of secondary and tertiary hyperparathyroidism. Arab J Intervent Radiol [serial online] 2019 [cited 2019 Aug 24 ];3:15-18
Available from: http://www.arabjir.com/article.asp?issn=2542-7075;year=2019;volume=3;issue=1;spage=15;epage=18;aulast=Nakarin;type=0